2016
Seifermann M, Epe B., Oxidatively generated base modifications in DNA: Not only carcinogenic risk factor but also regulatory mark? Free Radic Biol Med. 2016 Nov 18. pii: S0891-5849(16)31041-3. doi: 10.1016/j.freeradbiomed.2016.11.018. [Epub ahead of print]
Butzbach K, Rasse-Suriani FA, Gonzalez MM, Cabrerizo FM, Epe B., Albumin-Folate Conjugates for Drug-targeting in Photodynamic Therapy. Photochem Photobiol. 2016 Jul;92(4):611-9. doi: 10.1111/php.12602.
Allgayer J, Kitsera N, Bartelt S, Epe B, Khobta A., Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine. Nucleic Acids Res. 2016 Sep 6;44(15):7267-80. doi: 10.1093/nar/gkw473.
2015
Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP, Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintance of genetic stability after exposure to oxidative stress. Mol Cell Biol. 2015 Mar 2. pii:MCB.00134-15. [Epub ahead of print]
von der Lippen C, Sahu S, Seifermann M, Tiwari VK, Epe B, The repair of oxidized purines in the DNA of human lymphocytes requires an activation involving NF-YA-mediated upregulation of OGG1. DNA Repair (Amst). 2015 Jan;25:1-8. doi: 10.1016/j.dnarep.2014.10.008. Epub 2014Nov 5.
2014
Lühnsdorf B, Epe B, Khobta K, Excision of uracil from transcribed DNA negatively affects gene expression. J Biol Chem. 2014 Aug 8;289(32):22008-18. doi: 10.1074/jbc.M113.521807. Epub 2014 Jun 20.
Kitsera N, Gasteiger K, Lühnsdorf B, Allgayer J, Epe B, Carell T, Khobta A., Cockayne syndrome: varied requirement of transcription-coupled nucleotide excision repair for the removal of three structurally different adducts from transcribed DNA. PLoS One. 2014 Apr 8;9(4):e94405. doi: 10.1371/journal.pone.0094405. eCollection 2014.
Moritz E, Pauly K, Bravard A, Hall J, Radicella JP, Epe B., hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide. Carcinogenesis. 2014 Apr 8. [Epub ahead of print]
Vignoni M, Erra-Balsells R, Epe B, Cabrerizo FM., Intra- and extra-cellular DNA damage by harmine and 9-methyl-harmine. J Photochem Photobiol B. 2014 Mar 5;132:66-71. doi: 10.1016/j.jphotobiol.2014.01.020. Epub 2014 Feb 13.
2013
Butzbach K, Epe B., Photogenotoxicity of folic acid.Free Radic Biol Med. 2013 Aug 22;65C:821-827. doi: 10.1016/j.freeradbiomed.2013.08.168. [Epub ahead of print]
Allgayer J, Kitsera N, von der Lippen C, Epe B, Khobta A., Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence.Nucleic Acids Res. 2013 Oct 1;41(18):8559-8571. Epub 2013 Jul 17.
Vignoni M, Rasse-Suriani FA, Butzbach K, Erra-Balsells R, Epe B, Cabrerizo FM., Mechanisms of DNA damage by photoexcited 9-methyl-β-carbolines.Org Biomol Chem. 2013 Aug 28;11(32):5300-9. doi: 10.1039/c3ob40344k.
Keuser B, Khobta A, Gallé K, Anderhub S, Schulz I, Pauly K, Epe B., Influences of histone deacetylase inhibitors and resveratrol on DNA repair and chromatin compaction.Mutagenesis. 2013 Sep;28(5):569-76. doi: 10.1093/mutage/get034. Epub 2013 Jun 29.
Karunakaran SC, Ramaiah D, Schulz I, Epe B., Study of the mode and efficiency of DNA binding in the damage induced by photoactivated water soluble porphyrins.Photochem Photobiol. 2013 Sep;89(5):1100-5. doi: 10.1111/php.12088. Epub 2013 May 27.
2012
Fantini D, Moritz E, Auvré F, Amouroux R, Campalans A, Epe B, Bravard A, Radicella JP., Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments. DNA Repair (Amst). 2013 Mar 1;12(3):227-37
Lühnsdorf B., Kitsera, N., Warken D., Lingg T., Epe B., Khobta A., Generation of reporter plasmids containing defined base modifications in the DNA strand of choice. Anal Biochem. 2012 Jun 1; 425(1):47-53
Gonzalez MM, Vignoni M, Pellon-Maison M, Ales-Gandolfo MA, Gonzalez-Baro MR, Erra-Balsells R, Epe B, Cabrerizo FM., Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization. Org Biomol Chem. 2012 Mar 7;10(9):1807-19
2011
Kitsera N., Stathis D., Lühnsdorf B., Müller H., Carell T., Epe B., Khobta A., 8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1. Nucleic Acids Res. 2011 Mar 25.
Fusser M., Nesse G.J., Khobta A., Xia N., Li H., Klungland A., Epe B.: Spontaneous mutagenesis in Csb(m/m)Ogg1-(/)- mice is attenuated by resveratrol. Carcinogenesis. 2011 Jan;32(1):80-5
2010
Thierbach R., Drewes G., Fusser M., Voigt A., Kuhlow D., Blume U., Schulz T.J., Reiche C., Glatt H., Epe B., Steinberg P., Ristow M.: The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals. Biochem J. 2010 Oct 25;432(1):165-72
Khobta A., Lingg T., Schulz I., Warken D., Kitsera N., Epe B.: Mouse CSB protein is important for gene expression in the presence of a single-strand break in the non-transcribed DNA strand. DNA Repair. 2010 Sep 4;9(9):985-93
Khobta A., Anderhub S., Kitsera N., Epe B.: Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region. Nucleic Acids Res. 2010 Mar 24. in press
Amouroux R., Campalans A., Epe B., Radicella J.P.: Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions. Nucleic Acids Res. 2010 Jan 13. in press
Hariharan M., Karunakaran S.C. , Ramaiah D., Schulz I., Epe B.: Photoinduced DNA damage efficiency and cytotoxicity of novel viologen linked pyrene conjugates. Chem Commun (Camb). 2010 Mar 28;46(12):2064-6.
Becherel O.J., Jakob B., Cherry A.L., Gueven N., Fusser M., Kijas A.W., Peng C., Katyal S., McKinnon P.J., Chen J., Epe B., Smerdon S.J., Taucher-Scholz G., Lavin M.F.: CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response. Nucleic Acids Res. 2010 Mar 1;38(5):1489-503.
2009
Bravard A., Vacher M., Moritz E., Vaslin L., Hall J., Epe B., Radicella J.P.: Oxidation status of human OGG1-S326C polymorphic variant determines cellular DNA repair capacity. Cancer Res., 69(8):3642-9 (2009)
Guachalla L.M., Ju Z., Koziel R., von Figura G., Song Z., Fusser M., Epe B., Jansen-Dűrr P., Rudolph K. L.: Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging; 1(3): 303-315 (2009)
Khobta A., Kitsera N., Speckmann B., Epe B.: 8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein. DNA Repair ;8(3):309-17 (2009).
2008
Dittmar M., Knuth M., Beineke M., Epe B.: Role of Oxidative DNA Damage and Antioxidative Enzymatic Defence Systems in Human Aging The Open Anthropology Journal Vol. 1: 38-45 (2008)
Eiberger W., Volkmer B., Amouroux R., Dhérin C., Radicella J.P., Epe B: Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells. DNA Repair ; 7(6):912-21 (2008)
2007
Trapp, C., McCullough, A.K. and Epe, B.: The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1-/-/Csb-/-) mice. Mutation Res., 625,1-2, 155-63 (2007)
Kitsera, N. Khobta, A. and Epe, B.: Use of destabilized green fluorescent protein to sense the transcription block by genotoxic DNA lesions. BioTechniques, 43,2, 222-227 (2007)
Trapp, C. Schwarz, M. and Epe, B.: The peroxisome proliferator WY-14,643 promotes hepatocarcinogenesis caused by endogenously generated oxidative DNA base modifications in repair-deficient Csbm/m/Ogg1-/- mice. Cancer Res., 67, 5156-5161 (2007)
Suraweera, A. Becherel, O.J. Chen, P., Rundle, N., Woods, R., Nakamura J., Gatei, M., Criscuolo, C., Filla, A., Chessa, L., Fußer, M., Epe, B., Gueven, N. and Lavin, M.F.: Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. J. Cell Biol. 177, 969-979 (2007)
Bercht, M., Flohr-Beckhaus, C., Osterod, M., Rünger, T.M., Radicella, J.P. and Epe, B.: Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction? DNA Repair, 6, 367-373 (2007).
Trapp, C., Reite, K., Klungland A. and Epe, B.: Deficiency of Cockayne Syndome B (CSB) gene aggrevates the genomic instability caused by endogenous oxidative DNA base damage in mice. Oncogene, 26, 4044-4048 (2007).
Campalans, A., Amouroux, R., Bravard, A., Epe, B. and Radicella, J.P.: UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles. J Cell Sci. 120(Pt 1), 23-32 (2007).
Gueven, N., Becherel, O.J., Howe, O., Chen, P., Haince, J.F., Ouellet, M.E., Poirier, G.G., Waterhouse, N., Fußer, M., Epe, B., Ménissier de Murcia, J., de Murcia, G., McGowan, C.H., Parton, R., Mothersill, C., Grattan-Smith, P., Lavin, M.F.: A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance. Cell Death Diff., 14, 1149-1161 (2007)
Bockamp, E., Christel, C., Hameyer, D., Maringer, M, Reis, M., Heck, R., Cabezas-Wallscheid, N., Khobta, A., Epe, B., Oesch-Bartlomowicz, B., Kaina, B., Schmitt, S. and Eshkind, L.: Generation and characterisation of tTS-H4: a novel transcriptional repressor that is compatible with the reverse tetracycline-controlled TET-ON syst. J. Gene Med., 9, 308-318 (2007).
2006
Heine, T., Glatt H. and Epe, B.: Human cytochrome-P450 reductase can act as source of endogenous oxidative DNA damage and genetic instability. Free Rad. Biol. Med., 40, 801-807 (2006).
Damrot, J., Nübel, T., Epe, B., Roos, W.P., Kaina, B. and Fritz, B.: Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide. Br. J. Pharmacol. (2006), 1-10.
Ballmaier D, Epe B.: DNA damage by bromate: Mechanism and consequences. Toxicology. (2006).
2005
Hoffmann-Dorr S, Greinert R, Volkmer B, Epe B.: Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers. Mutat Res. 572, 142-9 (2005).
Sossou M, Flohr-Beckhaus C, Schulz I, Daboussi F, Epe B, Radicella JP.: APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability. Nucleic Acids Res. 12, 298-306 (2005).
Andersen S, Heine T, Sneve R, Konig I, Krokan HE, Epe B, Nilsen H.: Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts. Carcinogenesis 26, 547-55 (2005).
2004
Ramaiah, D., Eckert, I. , Arun, K.T., Lydia Weidenfeller, L. and Epe, B.: Squaraine dyes for photodynamic therapy: mechanism of cytotoxicity and DNA damage induced by halogenated squaraine dyes plus light (> 600 nm),Photochem. Photobiol. 79, 99-104 (2004).
Brendler-Schwaab, S., Czich, A., Epe, B., Gocke, E., Kaina, B., Müller, L., Pollet, D. and Utesch, D.: Photochemical genotoxicity: principles and test methods. Mutat Res. 566,:65-91 (2004).
Hoffmann, S., Spitkovsky, D., Radicella, J.P., Epe, B. and Wiesner, R.J.: Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of mammalian cells, Free Radical Biol. Med. 36, 765-773 (2004).
2003
Rhodes, L.E., Shahbakhti, H., Azurdia, R.M., Moison, R.M.W., Steenwinkel, M.-J., Homburg, M.I., Dean, M.P., McArdle, F., Beijersbergen van Henegouwen, G.M.J., Epe, B. and Vink, A.A. (2003): Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers. Carcinogenesis 24, 919-925.
Hengstler J.G., Bolm-Audorff U., Faldum A., Janssen K., Reifenrath M., Gotte W., Jung D., Mayer-Popken O., Fuchs J., Gebhard S., Bienfait H.G., Schlink K., Dietrich C., Faust D., Epe B., Oesch F.: Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis 24, 63-73 (2003).
Rünger T.M., Kotas M, Poot M, Leverkus M, Epe B, Jeggo PA, Hellfritsch D (2003): Reduced joining of DNA ends correlates with chromosomal instability in three melanoma cell lines. Tumour Biol. 24,100-108.
Flohr, C. Bürkle, A., Radicella, J.P., and Epe, B.: Poly(ADP-ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein, Nucleic Acids Res.,31, 5332-5337 (2003).
2002
Phoa, N. and Epe, B. (2002) Influence of nitric oxide on the generation and repair of oxidative DNA damage in mammalian cells. Carcinogenesis, 23, 469-475. Arun, K.T., Epe, B. and Ramaiah, D. (2002): Aggregation behavior of halogenated squaraine dyes in buffer, electrolytes, organized media and DNA. J. Phys. Chem. B. 106, 11622-11627.
Epe, B.: Role of endogenous oxidative DNA damage in carcinogenesis: what can we learn from repair-deficient mice?" Biol. Chem., 383, 467-475 (2002). Osterod, M., E. Larsen, F. Le Page, J.G. Hengstler G.T.J. van der Horst, S. Boiteux, A. Klungland, and B. Epe: A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage. Oncogene,21, 8232-8239 (2002).
Ramaiah, D., Eckert, I., Arun, K.T., Weidenfeller, L. and Epe, B.: Squaraine dyes for photodynamic therapy: study of their cytotoxicity and genotoxicity in bacteria and mammalian cells. Photochem. Photobiol., 76, 672-677 (2002).
Arun, K.T., Epe, B. and Ramaiah, D.: Aggregation behavior of halogenated squaraine dyes in buffer, electrolytes, organized media and DMA. J. Phys. Chem. B 106, 11622-11627 (2002).
2001
Mahler, H.-C., Schultz, I., Adam, W., Grimm, G.N., Saha-Möller, C.R. and Epe, B.: tert-Butoxyl radicals generate mainly 7,8-dihydro-8-oxoguanine in DNA. Mutat. Res., 461, 289-299 (2001).
Osterod, M., Hollenbach, S., Hengstler, J.G., Barnes, D.E., Lindahl, T. and Epe, B. (2001) Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-hydroxyguanine-DNA glycosylase (Ogg1) deficient mice. Carcinogenesis, 22, 1459-1463.
2000
Rünger, T.M., Emmert, S., Schadendorf, D., Diem, C., Epe, B., Hellfritsch D.: Alterations of DNA repair in melanoma cell lines resistant to cisplatin, fotemustine, or etoposide. J. Invest. Dermatol.,114, 34-39 (2000).
Schulz, I., Mahler, H.-C., Boiteux, S. and Epe, B.: Oxidative DNA base damage induced by singlet oxygen and photosensitization: recognition by repair endonucleases and mutagenicity. Mutat. Res., 461, 145-156 (2000).
1999
Will, O., H.-C. Mahler, A.-P. Arrigo and B. Epe: Influence of glutathione levels and heat-shock on the steady-state levels of oxidative DNA base modifications in mammalian cells. Carcinogenesis 20, 333-337 (1999).
Hollenbach, S., A. Dhénault, I. Eckert, J. P. Radicella and B. Epe: Overexpression of OGG1 in mammalian cells: effects on induced and spontaneous oxidative DNA damage and mutagenesis. Carcinogenesis 20, 1863-1868 (1999).
Will, O., Gocke, E., Eckert, I., Schulz, I., Pflaum, M., Mahler, H.C. and Epe, B.: Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022. Mutat. Res., 435, 89-101 (1999).
Klungland, A., Rosewell, I., Hollenbach, S., Larsen, E., Daly, G., Epe, B., Seeberg, E., Lindahl, T. and Barnes, D.E.: Accumulation of pre-mutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl. Acad. Sci. USA, 96, 13300-13305 (1999).
1998
Pflaum, M., C. Kielbassa, M. Garmyn and B. Epe: Oxidative DNA damage induced by visible light in mammalian cells: extent, inhibition by antioxidants and genotoxic effects. Mutat. Res., 408, 137-146 (1998).
Will, O., D. Schindler, S. Boiteux and B. Epe: Fanconi´s anaemia cells have normal steady-state levels and repair of oxidative base modifications sensitive to Fpg protein. Mutat. Res., 409, 65-72 (1998).
Pflaum, M., O. Will, H.-C. Mahler and B. Epe: DNA oxidation products determined with repair endonucleases in mammalian cell: types, basal levels and influence of cell proliferation. Free Radical Res., 29, 585-594 (1998).
1997
Ballmaier, D., M. Pflaum, C. Kielbassa and B. Epe: Oxidative DNA damage profiles in mammalian cells. Recent Res. Cancer Res., 143, 35-47 (1997).
Adam, W., S. Andler, D. Ballmaier, S. Emmert, B. Epe, G. Grimm, K. Mielke, M. Möller, T.M. Rünger, C.R. Saha-Möller, A. Schönberger and H. Stopper: Oxidative DNA damage induced by dioxetanes, photosensitizing ketones and photo-Fenton reagents. Recent Res. Cancer Res., 143, 21-34 (1997).
Kielbassa, C., L. Roza and B. Epe: Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis 18, 811-816 (1997).
Adam, W., P. Groer, K. Mielke, C.R. Saha-Möller, R. Hutterer, W. Kiefer, V. Nagel, F.W. Schneider, D. Ballmaier, Y. Schleger and B. Epe: Photochemical and photobiological studies with acridine and phenanthridine hydroperoxides in cell-free DNA. Photochem. Photobiol., 66, 26-33 (1997).
Adam, W., K. Mielke, C.R. Saha-Möller, M. Möller, H. Stopper, R. Hutterer, D. Ballmaier, Y. Schleger and B. Epe: Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analogon in cell-free and cellular DNA. Photochem. Photobiol., 66, 46-54 (1997).
Collins, A., J. Cadet, B. Epe and C. Gedik: Problems in the measurement of 8-hydroxyguanine in human DNA. Report on a workshop, DNA oxidation, held in Aberdeen, UK, January 19-21, 1997, Carcinogenesis 18, 1833-1836.
Pflaum, M., O. Will and B. Epe: Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases. Carcinogenesis 18, 2225-2231 (1997).
1996
Poot, M., O. Gross, B. Epe, M. Pflaum and H. Hoehn: Cell cycle defect in connection with oxygen and iron sensitivity in Fanconi anemia lymphoblastoid cells. Exp. Cell Res. 222, 262-268 (1996).
Epe, B., D. Ballmaier, W. Adam, G. Grimm and C.R. Saha-Möller: Photolysis of N-hydroxypyridinethiones: a new source of hydroxyl radicals for the direct damage of cell-free and cellular DNA. Nucleic Acids Res. 24, 1625-1631 (1996).
Adam, W., M. Berger, J. Cadet, F. Dall´Acqua, B. Epe, S. Frank, D. Ramaiah, S. Raoul, C.R. Saha-Möller and D. Vedaldi: Photochemistry and photobiology of furocoumarin-hydroperoxides derived from imperatorin: novel intercalating photo-Fenton reagents for oxidative DNA modification by hydroxyl radicals. Photochem. Photobiol. 63, 768-778 (1996).
Epe, B., D. Ballmaier, I. Roussyn, K. Briviba and H. Sies: DNA damage by peroxynitrite characterized with repair enzymes. Nucleic Acids Res. 24, 4105-4110 (1996).
199
Ballmaier, D. and B. Epe: Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells. Carcinogenesis, 16, 335-342 (1995).
Adam, W., J. Cadet, F. Dall´Acqua, B. Epe, D. Ramaiah and C. Saha-Möller: Photosensitized formation of 8-hydroxy-2´-deoxyguanosine in Salmon testes DNA by furocoumarin hydroperoxides: a novel, intercalating "photo-Fenton" reagent for oxidative DNA damage. Angew. Chem. Int. Ed. Engl. 34, 107-109 (1995).
Emmert, S., B. Epe, C.R. Saha-Möller, W. Adam and T.M. Rünger: Assessment of genotoxicity and mutagenicity of 1,2-dioxetanes in human cells using a plasmid shuttle vector. Photochem. Photobiol. 61, 136-141 (1995).
Rünger, T.M., B. Epe and K. Mölling: Repair of ultraviolet B and singlet oxygen-induced DNA damage in xeroderma pigmentosum cells. J. Invest. Dermatol. 104, 68-73 (1995).
Legrand-Poels, S., V. Bours, B. Piret, M. Pflaum, B. Epe, B. Rentier and J. Piette: Transcription factor NF-kB is activated by photosensitization generating oxidative DNA damages. J. Biol. Chem. 270, 6925-6934 (1995).
Adam, W., D. Ballmaier, B. Epe, G.N. Grimm and C.R. Saha-Möller: N-Hydroxypyridinethiones as photochemical hydroxyl radical sources for oxidative DNA damage. Angew. Chem. Int. Ed. Engl. 34, 2156-2158 (1995).
Möller, M., H. Stopper, M. Häring, Y. Schleger, B. Epe, W. Adam and C.R. Saha-Möller: Genotoxicity induced by furocoumarin hydroperoxides in mammalian cells upon UVA irradiation. Biochem. Biophys. Res. Commun. 216, 693-701 (1995).
1994
Pflaum, M., S. Boiteux and B. Epe: Visible light generates oxidative DNA base modifications in high excess of strand breaks in mammalian cells. Carcinogenesis, 15, 297-300 (1994).
Häring, M., H. Rüdiger, B. Demple, S. Boiteux and B. Epe: Recognition of oxidized abasic sites by repair endonucleases. Nucleic Acids Res., 22, 2010-2015 (1994).
1993
Epe, B., M. Pflaum and S. Boiteux: DNA damage induced by photosensitizers in cellular and cell-free systems. Mutation Res. 299, 135-145 (1993).
Epe, B., M. Pflaum, M. Häring, J. Hegler and H. Rüdiger: Use of repair endonucleases to characterize DNA damage induced by reactive oxygen species in cellular and cell-free systems. Toxicol. Lett. 67, 57-72 (1993).
Adam, W., Ahrweiler, M., Saha-Möller, C.R., Sauter, M., Schönberger, A., Epe, B., Müller, E., Schiffmann, D., Stopper, H. and Wild, D.: Genotoxicity studies of benzofuran dioxetanes and epoxides with isolated DNA, bacteria and mammalian cells. Toxicol. Lett. 67, 41-55 (1993).
Epe, B., H. Henzl, W. Adam and C.R. Saha-Möller: Endonuclease-sensitive DNA modifications induced by acetone and acetophenone as photosensitizers. Nucleic Acids Res. 21, 863-869 (1993).
Adam,W., Th. Mosandl, D. Ramaiah, C.R. Saha-Möller, B. Epe and D. Wild: Furocoumarin dioxetanes and hydroperoxides as novel photobiological DNA-damaging agents. Quimica nova, 16, 316-319 (1993).
Epe, B., M. Häring, D. Ramaiah, H. Stopper, W. Adam, M.M. Abou-Elzahab and C.R. Saha-Möller: DNA damage induced by furocoumarin hydroperoxides plus UV (360 nm). Carcinogenesis, 14, 2271-2276 (1993).
Hegler, J., D. Bittner, S. Boiteux and B. Epe: Quantification of oxidative DNA modifications in mitochondria. Carcinogenesis, 14, 2309-2312 (1993).
1992
Poot, M., B. Epe and H. Hoehn: Cell cycle effects of the DNA topoisomerase inhibitors camptothecin and m-AMSA in lymphoblastoid cell lines from patients with Fanconi anemia, Mutation Res. 270, 185-189 (1992).
Epe, B., E. Müller, W. Adam and C.R. Saha-Möller: Photochemical DNA modifications induced by 1,2-dioxetanes. Chem.-Biol. Interactions, 85, 265-281 (1992).
1991
Henschler, D., E. Eder, B. Epe and D. Schiffmann: Genotoxic and cell-transforming properties of (trans, trans)- muconaldehyde. Mutation Res. 248, 35-43 (1991).
1990
Epe, B. U. Harttig, H. Stopper and M. Metzler: Covalent binding of reactive estrogen metabolites to microtubular protein as a possible mechanism of aneuploidy induction and neoplastic cell transformation. Environ. Health Perspect. 88, 123-127 (1990).
Epe, B., J. Hegler and D. Wild: Identification of ultimate DNA damaging oxygen species. Environ. Health Perspect. 88, 111-115 (1990).
Adam, W., A. Beinhauer, Th. Mosandl, Ch. Saha-Möller, F. Vargas, B. Epe, E. Müller, D. Schiffmann and D. Wild: Photobiological studies with dioxetanes in isolated DNA, bacteria and mammalian cells. Environ. Health Perspect. 88, 89-97 (1990).
Müller, E., S. Boiteux, R.P. Cunningham and B. Epe: Enzymatic recognition of DNA modifications induced by singlet oxygen and photosensitizers. Nucl. Acids Res. 18, 5969-5973 (1990).